Item no. |
ICH4023-20MG |
Manufacturer |
IchorBio
|
Amount |
20 mg |
Quantity options |
100 mg
10 mg
1 mg
20 mg
50 mg
5 mg
|
Category |
|
Type |
Biosimilars |
Specific against |
Human (Homo sapiens) |
Host |
Humanized |
Isotype |
IgG |
Purity |
>95% by SDS-PAGE and HPLC |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Proprotein convertase subtilisin/kexin type 9, <br />NARC-1, PC9 |
Shipping condition |
Cool pack |
Available |
|
Specificity |
Detects human PCSK9. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Evolocumab. This product is for research use only. |
Manufacturer - Category |
Low endotoxin, Biosimilar, recombinant antibody |
Manufacturer - Isotype |
Human IgG2 |
Manufacturer - Targets |
PCSK9 |
Manufacturer - Host |
Humanized |
Shipping Temperature |
Blue ice |
Storage Conditions |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Background |
Evolocumab biosimilar is a human monoclonal immunoglobulin G2 (IgG2) directed against human proprotein convertase subtilisin kexin 9 (PCSK9). Evolocumab biosimilarhas an approximate molecular weight (MW) of 144 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells. |
Concentration |
1.0 - 5.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Detects human PCSK9. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Evolocumab. |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Isotype Control |
Bulk Human IgG2 Isotype Control (IB2) [ICH2255] |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.