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Evolocumab Biosimilar - Research Grade

Evolocumab Biosimilar - Research Grade

Item no.	ICH4023-1mg
Manufacturer	IchorBio
Amount	1 mg
Quantity options	100 mg 10 mg 1 mg 20 mg 50 mg 5 mg
Category	Antibodies In Vivo Antibodies
Type	Biosimilars
Specific against	Human (Homo sapiens)
Host	Humanized
Isotype	IgG
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Proprotein convertase subtilisin/kexin type 9, <br />NARC-1, PC9
Shipping condition	Cool pack
Available
Specificity	Detects human PCSK9. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Evolocumab.
Manufacturer - Category	Low endotoxin, Biosimilar, recombinant antibody
Manufacturer - Isotype	Human IgG2
Manufacturer - Targets	PCSK9
Manufacturer - Host	Humanized
Shipping Temperature	Blue ice
Storage Conditions	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation	Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Background	Evolocumab biosimilar is a human monoclonal immunoglobulin G2 (IgG2) directed against human proprotein convertase subtilisin kexin 9 (PCSK9). Evolocumab biosimilarhas an approximate molecular weight (MW) of 144 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells.
Concentration	1.0 - 5.0 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Detects human PCSK9. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Evolocumab.
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control	Bulk Human IgG2 Isotype Control (IB2) [ICH2255]
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 2/7/2025

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