Item no. |
ICH4011-5MG |
Manufacturer |
IchorBio
|
Amount |
5mg |
Category |
|
Type |
Biosimilars |
Specific against |
Human |
Host |
Humanized |
Isotype |
IgG1 Kappa |
Purity |
>95% by SDS-PAGE and HPLC |
Citations |
Narsimhan et al. Mobile Affinity Selection Chromatography Analysis of Therapeutic Monoclonal Antibodies. Analytical Chemistry |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, MS4A1 |
Available |
|
Specificity |
Detects human CD20. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Rituximab. This product is for research use only. |
Manufacturers Product Category |
Low endotoxin, biosimilar antibody |
Isotype Information |
Human IgG1 Kappa |
Host Information |
Humanized |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Background |
Rituximab is a genetically engineered chimeric murine/human monoclonal IgG1 kappa antibody directed against the CD20 antigen. Rituximab has an approximate molecular weight of 145 kD. Rituximab is produced by mammalian cell (Chinese Hamster Ovary). |
Concentration |
1.0 - 5.0 mg/ml |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Endotoxin |
≤ 0.5 EU/mg as determined by the LAL method |
Storage |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.