Item no. |
ICH4008-20MG |
Manufacturer |
IchorBio
|
Amount |
20mg |
Category |
|
Type |
Biosimilars |
Specific against |
Human |
Host |
Humanized |
Isotype |
IgG1 Kappa |
Purity |
>95% by SDS-PAGE and HPLC |
Citations |
Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1 |
Available |
|
Specificity |
Detects human EGFR. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Nimotuzumab. This product is for research use only. |
Manufacturers Product Category |
Low endotoxin, biosimilar antibody |
Isotype Information |
Human IgG1 Kappa |
Host Information |
Humanized |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Background |
Nimotuzumab biosimilar has a humanized human-mouse h-R3 heavy chain and a humanized human-mouse h-R3κ-chain. nimotuzumab binds to the epidermal growth factor receptor (EGFR), a signalling protein that normally controls cell division. |
Concentration |
1.0 - 5.0 mg/ml |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Endotoxin |
≤ 0.5 EU/mg as determined by the LAL method |
Storage |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.