Item no. |
ICH4007-5MG |
Manufacturer |
IchorBio
|
Amount |
5 mg |
Quantity options |
100 mg
10 mg
1 mg
20 mg
50 mg
5 mg
|
Category |
|
Type |
Biosimilars |
Specific against |
Human (Homo sapiens) |
Host |
Humanized |
Isotype |
IgG1 |
Purity |
>95% by SDS-PAGE and HPLC |
Citations |
Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1 |
Shipping condition |
Cool pack |
Available |
|
Specificity |
Detects human EGFR. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Matuzumab. This product is for research use only. |
Manufacturer - Category |
Low endotoxin, Biosimilar, recombinant antibody |
Manufacturer - Isotype |
Human IgG1 |
Manufacturer - Targets |
EGFR |
Manufacturer - Host |
Humanized |
Shipping Temperature |
Blue ice |
Storage Conditions |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Background |
Matuzumab biosimilar is a humanized IgG1 monoclonal antibody against human EGFR. As it only has approximately 10% murine origin it has limited immunogenicity, and being IgG1 it is capable of inducing antibody dependent cell cytotoxicity (ADCC).Matuzumab biosimilar is produced in mammalian (Chinese hamster ovary) cell culture. |
Concentration |
1.0 - 5.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Detects human EGFR. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Matuzumab. |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Isotype Control |
Bulk Human IgG1 Isotype Control (IB1) [ICH2254] |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.