Item no. |
ICH4004-50MG |
Manufacturer |
IchorBio
|
Amount |
50 mg |
Quantity options |
100 mg
10 mg
1 mg
20 mg
50 mg
5 mg
|
Category |
|
Type |
Biosimilars |
Specific against |
Human (Homo sapiens) |
Host |
Humanized |
Isotype |
IgG1 |
Purity |
>95% by SDS-PAGE and HPLC |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1 |
Shipping condition |
Cool pack |
Available |
|
Specificity |
Detects human EGFR. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Cetuximab. This product is for research use only. |
Manufacturer - Category |
Low endotoxin, Biosimilar, recombinant antibody |
Manufacturer - Isotype |
Human IgG1 |
Manufacturer - Targets |
EGFR |
Manufacturer - Host |
Humanized |
Shipping Temperature |
Blue ice |
Storage Conditions |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Background |
Cetuximab biosimilar is a recombinant, human/mouse chimeric monoclonal antibody that binds specifically to the extracellular domain of the human epidermal growth factor receptor (EGFR). Cetuximab biosimilar is composed of the Fv regions of a murine anti-EGFR antibody with human IgG1 heavy and kappa light chain constant regions and has an approximate molecular weight of 152 kDa. Cetuximab biosimilar is produced in mammalian (Chinese Hamster Ovary) cell culture. |
Concentration |
1.0 - 5.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Detects human EGFR. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Cetuximab. |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Isotype Control |
Bulk Human IgG1 Isotype Control (IB1) [ICH2254] |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.