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Adalimumab Biosimilar - Research Grade

Adalimumab Biosimilar - Research Grade

Item no.	ICH4001-5MG
Manufacturer	IchorBio
Amount	5mg
Category	Antibodies In Vivo Antibodies
Type	Biosimilars
Specific against	Human
Host	Humanized
Isotype	IgG1 Kappa
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2
Available
Specificity	Detects human TNF alpha. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Adalimumab. This product is for research use only.
Manufacturers Product Category	Low endotoxin, biosimilar antibody
Isotype Information	Human IgG1 Kappa
Host Information	Humanized
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution	Activated monocytes, neutrophils, macrophages, T cells, B cells, NK cells, LAK cells
Background	Adalimumab biosimilar is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor (TNF)，was created using phage display technology resulting in an antibody with human derived heavy and light chain variable regions and human IgG1:k constant regions. Adalimumab biosimilar is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) expression system and is purified by a process that includes specific viral inactivation and removal steps. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.
Concentration	1.0 - 5.0 mg/ml
Formulation	Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Endotoxin	≤ 0.5 EU/mg as determined by the LAL method
Storage	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 12/20/2024

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