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Anti-Mouse PD-L1 (10F.9G2) In Vivo Antibody - Low Endotoxin

Anti-Mouse PD-L1 (10F.9G2) In Vivo Antibody - Low Endotoxin

Item no.	ICH1086-100MG
Manufacturer	IchorBio
Amount	100 mg
Quantity options	100 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Antibodies In Vivo Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Melanoma Sarcoma Mesothelioma Flow Cytometry Blocking
Type	Antibody
Applications	FC, IF, IHC, Blocking, FA
Clone	10F.9G2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Purity	>95% by SDS-PAGE and HPLC
Citations	p16-dependent upregulation of PD-L1 impairs immunosurveillance of senescent cells Chen et al. NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer. Advanced Science Lin et al. Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice. Cell Reports
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Programmed cell death 1 ligand 1, Cd274, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Shipping condition	Cool pack
Available
Specificity	Anti-PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2) recognizes an epitope on Mouse CD274
Manufacturer - Applications	Flow Cytometry, Blocking, IHC (Frozen), Immunofluorescence, Functional Assays
Manufacturer - Category	Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype	Rat IgG2b Kappa
Manufacturer - Targets	PD-L1
Shipping Temperature	Blue ice
Storage Conditions	anti-PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2) is stable when stored at 2-8°C. Do not freeze.
Aggregation	Aggregation level ≤ 5%
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution	The CD274 antigien is present on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	CD274, also known as B7-H1 and PD-L1, is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes.
Concentration	1.0 - 5.0 mg/ml
Endotoxin	<1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Anti-PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2) recognizes an epitope on Mouse CD274
Purification method	This monoclonal antibody was purified using Protein G
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	Unknown
Related Antibodies	ICH1086UL-5MG
Isotype Control	Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 2/7/2025

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