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Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin (GL1)

Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin (GL1)

Item no.	ICH1038-5MG
Manufacturer	IchorBio
Amount	5mg
Category	Antibodies In Vivo Antibodies Western Blot Blocking
Type	Antibody
Applications	WB, FC, IP, IHC, ICC, Blocking
Clone	GL1
Specific against	Mouse
Host	Rat
Isotype	IgG2a Kappa
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1
Available
Specificity	Anti-CD86 In Vivo Antibody - Low Endotoxin (GL1) recognizes an epitope on Mouse CD86
Manufacturers Product Category	Low Endotoxin, anti-mouse
Isotype Information	Rat IgG2a Kappa
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution	B cells and T cells (upregulated upon activation), macrophages, dendritic cells, and astrocytes
Background	CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the Ig gene superfamily. CD86 is a ligand for CD28 and CD152 (CTLA-4). CD86 is related to the CD80 molecule and functions as a counterreceptor for CD28 and CTLA-4. The GL1 clone has been shown to provide critical signals for T-Cell-dependent responses in vivo and in vitro.
Immunogen	LPS-activated CBA/Ca mouse splenic B cells
Concentration	1.0 mg/ml
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 5%
Storage	anti-CD86 In Vivo Antibody - Low Endotoxin (GL1) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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