Comparison
Antibodies

Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin (GL1) European Partner

Item no. ICH1038-25MG
Manufacturer IchorBio
Amount 25mg
Category
Type Antibody
Applications WB, FC, IP, IHC, ICC, Blocking
Clone GL1
Specific against Mouse
Host Rat
Isotype IgG2a Kappa
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1
Available
Specificity Anti-CD86 In Vivo Antibody - Low Endotoxin (GL1) recognizes an epitope on Mouse CD86
Manufacturers Product Category
Low Endotoxin, anti-mouse
Isotype Information
Rat IgG2a Kappa
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution
B cells and T cells (upregulated upon activation), macrophages, dendritic cells, and astrocytes
Background
CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the Ig gene superfamily. CD86 is a ligand for CD28 and CD152 (CTLA-4). CD86 is related to the CD80 molecule and functions as a counterreceptor for CD28 and CTLA-4. The GL1 clone has been shown to provide critical signals for T-Cell-dependent responses in vivo and in vitro.
Immunogen
LPS-activated CBA/Ca mouse splenic B cells
Concentration
1.0 mg/ml
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Aggregation
Aggregation level ≤ 5%
Storage
anti-CD86 In Vivo Antibody - Low Endotoxin (GL1) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25mg
Available: In stock
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