Item no. |
ICH1037UL-5MG |
Manufacturer |
IchorBio
|
Amount |
5 mg |
Quantity options |
100 mg
25 mg
50 mg
5 mg
|
Category |
|
Type |
Antibody |
Applications |
WB |
Clone |
16-10A1 |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
Hamster - Armenian |
Isotype |
IgG |
Purity |
>98% by SDS-PAGE and HPLC |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Activation B7-1 antigen, B7 |
Shipping condition |
Cool pack |
Available |
|
Specificity |
Anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1) recognizes an epitope on Mouse CD80 |
Manufacturer - Applications |
Western Blot |
Manufacturer - Category |
Ultra-Low Endotoxin, anti-mouse, monoclonal antibody |
Manufacturer - Isotype |
Armenian Hamster IgG |
Manufacturer - Targets |
CD80 |
Shipping Temperature |
Blue ice |
Storage Conditions |
anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Aggregation |
Aggregation level ≤ 1% |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
Antigen Distribution |
Mouse CD80 is expressed on Activated B-Cells, Activated T-Cells, macrophages, and dendritic cells. |
Application Notes |
Each investigator should determine their own optimal working dilution for specific applications. |
Background |
CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86. |
Concentration |
≥ 2.0 mg/ml |
Endotoxin |
≤ 0.5 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Anti-CD80 In Vivo Antibody - Ultra Low Endotoxin (16-10A1) recognizes an epitope on Mouse CD80 |
Purification method |
This monoclonal antibody was purified using Protein A |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Immunogen |
Purified Recombinant Mouse CD80 (>98%) |
IMPACT Pathogen Test |
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Hamster parvovirus Lymphocytic choriomeningitis Minute virus of mice Theiler's murine encephalomyelitis virus Sendai virus Reovirus 3 Hantaan virus |
Related Antibodies |
|
Isotype Control |
Armenian Hamster IgG Isotype Control for In Vivo - Ultra Low Endotoxin [PIP] (ICH2251UL) |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.