Comparison

Bulk Anti-Human HLA-DR (L243) Antibody European Partner

Item no. ICH1026-25MG
Manufacturer IchorBio
Amount 25 mg
Quantity options 100 mg 1 mg 25 mg 50 mg 5 mg
Category
Type Antibody
Applications WB, FC, IP, IHC, Blocking
Clone L243
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a
Purity >95% by SDS-PAGE and HPLC
Citations WNT4 promotes macrophage polarization via
granulosa cell M-CSF and reduces granulosa cell
apoptosis in endometriosis
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Major Histocompatibility Class II, MHC class II, HLA-DR Monomorphic
Shipping condition Cool pack
Available
Specificity Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ
Manufacturer - Applications
Western Blot, Blocking, Flow Cytometry, Immunoprecipitation, CyTOF, IHC (Frozen)
Manufacturer - Category
Low Endotoxin, anti-human, monoclonal antibody
Manufacturer - Isotype
Mouse IgG2a
Manufacturer - Targets
HLA-DR
Shipping Temperature
Blue ice
Storage Conditions
anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) is stable for at least four (4) weeks when stored at 2-8°C. For long-term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Aggregation
Aggregation level ≤ 5%
Formulation
No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4.
Antigen Distribution
The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas.
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Background
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Aβ heterodimer.
Concentration
1.0 mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ
Purification method
This monoclonal antibody was purified using Protein A
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen
Unknown
Isotype Control
Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close