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Anti-Human HLA-DR In Vivo Antibody - Low Endotoxin (L243)

Anti-Human HLA-DR In Vivo Antibody - Low Endotoxin (L243)

Item no.	ICH1026-1MG
Manufacturer	IchorBio
Amount	1mg
Category	Oncology Antibodies In Vivo Antibodies By Cell Type Carcinoma Western Blot Blocking
Type	Antibody
Applications	WB, Blocking
Clone	L243
Specific against	Human
Host	Mouse
Isotype	IgG2a
Purity	>95% by SDS-PAGE and HPLC
ECLASS 5.1	32160702
ECLASS 6.1	32160702
ECLASS 8.0	32160702
ECLASS 9.0	32160702
ECLASS 10.0.1	32160702
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	in vivo
Available
Specificity	Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ
Aggregation	Aggregation level <= 5%
Antigen Distribution	The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Abeta heterodimer.
Concentration	1.0 mg/ml
Endotoxin	<= 1.0 EU/mg as determined by the LAL method
Formulation	No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4.
Immunogen	Unknown
Product Type	Low Endotoxin, anti-human
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Storage	anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) is stable for at least four (4) weeks when stored at 2-8C. For long-term storage, aliquot in working volumes without diluting and store at - 20C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

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Delivery expected until 8/16/2024

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