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Bulk Anti-Human HLA-DR (L243) Antibody

Bulk Anti-Human HLA-DR (L243) Antibody

Item no.	ICH1026-100MG
Manufacturer	IchorBio
Amount	100 mg
Quantity options	100 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Antibodies In Vivo Antibodies By Cell Type Carcinoma Western Blot Blocking
Type	Antibody
Applications	WB, FC, IP, IHC, Blocking
Clone	L243
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Purity	>95% by SDS-PAGE and HPLC
Citations	WNT4 promotes macrophage polarization via granulosa cell M-CSF and reduces granulosa cell apoptosis in endometriosis
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Major Histocompatibility Class II, MHC class II, HLA-DR Monomorphic
Shipping condition	Cool pack
Available
Specificity	Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ
Manufacturer - Applications	Western Blot, Blocking, Flow Cytometry, Immunoprecipitation, CyTOF, IHC (Frozen)
Manufacturer - Category	Low Endotoxin, anti-human, monoclonal antibody
Manufacturer - Isotype	Mouse IgG2a
Manufacturer - Targets	HLA-DR
Shipping Temperature	Blue ice
Storage Conditions	anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) is stable for at least four (4) weeks when stored at 2-8°C. For long-term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Aggregation	Aggregation level ≤ 5%
Formulation	No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4.
Antigen Distribution	The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Aβ heterodimer.
Concentration	1.0 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ
Purification method	This monoclonal antibody was purified using Protein A
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	Unknown
Isotype Control	Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 2/7/2025

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