Comparison

CDK1-IN-5 European Partner

Item no. HY-151409-1ea
Manufacturer MedChem Express
CASRN 3032997-20-6
Amount 1 ea
Category
Type Biosimilars
Specific against other
Formula C27H26ClN5OS
Citations [1]Akl L, et al. Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer. Eur J Med Chem. 2022 Aug 31;243:114704.
Smiles S=C(N1CCN(C2=NN=C(CC3=CC=C(OC)C=C3)C4=C2C=CC=C4)CC1)NC5=CC=CC(Cl)=C5
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Available
Product Description
CDK1-IN-5 (10h) is a selective CDK1 inhibitor with IC50s of 42.19, 188.71 and 354.15 nM for CDK1, CDK2 and CDK5, respectively. CDK1-IN-5 inhibits growth of cancer cells by affecting cell cycle. CDK1-IN-5 can be used for the research of cancer[1].
Shipping
Room temperature
Manufacturers Applications
Cancer-Kinase/protease
MolecularWeight
504.05
Clinical Information
No Development Reported
Manufacturers Research Area
Cancer
Solubility
10 mM in DMSO
Target
CDK
Manufacturers Target
CDK
Isoform
CDK1; CDK2; CDK5
Manufacturers Pathway
Cell Cycle/DNA Damage
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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