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AF/LE Purified Anti-Human CD11a Antibody[R7-1]

AF/LE Purified Anti-Human CD11a Antibody[R7-1]

Item no.	E-AB-F12110-500
Manufacturer	Elabscience
Amount	500 ug
Quantity options	1 mg 100 mg 100 ug 25 mg 25 ug 50 ug 500 ug 5 mg
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Adhesion Molecules Antibodies Obesity Flow Cytometry Primary Antibodies Functional Assays Other Lipid\Cholesterol Metabolism Modulators
Type	Antibody Monoclonal
Applications	FC, FA
Clone	R7-1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Integrin alpha-L, LFA-1A, CD11A, ITGAL,
Similar products	ITGAL, CD11A, Integrin alpha-L, LFA-1A
Shipping condition	Cool pack
Available
Manufacturer - Category	Flow Cytometry Antibodies
Manufacturer - Isotype	Mouse IgG1, κ
Manufacturer - Conjugate / Tag	None (AF/LE)
Shipping Temperature	Ice bag
Storage Conditions	Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Background	CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
Concentration	≥1 mg/mL
Buffer	Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
Abbreviation	CD11a
Clonality	Monoclonal
Usage	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 5/8/2025

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