Comparison

AF/LE Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3]

Item no. E-AB-F11330-1
Manufacturer Elabscience
Amount 1 mg
Quantity options 1 mg 100 mg 100 ug 25 mg 25 ug 50 ug 500 ug 5 mg
Category
Type Antibody Monoclonal
Applications FC, Blocking, FA
Clone 29E.2A3
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b Kappa
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias B7-H1, PD-L1, Programmed cell death ligand 1, B7 homolog 1, B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,
Similar products B7H1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, PD-L1, B7-H, B7-H1, Programmed cell death ligand 1
Shipping condition Cool pack
Available
Manufacturer - Category
Flow Cytometry Antibodies
Manufacturer - Isotype
Mouse IgG2b, κ
Manufacturer - Conjugate / Tag
None (AF/LE)
Shipping Temperature
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Background
CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Concentration
≥1 mg/mL
Buffer
Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
Abbreviation
PD-L1
Clonality
Monoclonal
Usage
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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