Item no. |
CSB-RA159926A0HU-100ul |
Manufacturer |
Cusabio
|
Amount |
100ul |
Category |
|
Type |
Antibody Monoclonal |
Format |
Liquid |
Applications |
WB, IHC, ELISA |
Clone |
5G11 |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
ATP synthase subunit alpha, mitochondrial, ATP5A1, ATP5A ATP5AL2 ATPM, ATP synthase subunit alpha, mitochondrial, ATP5A1, ATP5A ATP5AL2 ATPM |
Similar products |
ATP5A1, mitochondrial, ATP synthase subunit alpha, ATP5A ATP5AL2 ATPM |
Available |
|
UniProt ID |
P25705 |
Immunogen |
A synthesized peptide derived from human ATP5A1 |
Tested Applications |
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200 |
Background |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity). |
Conjugate |
Non-conjugated |
Buffer |
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage |
Upon receipt, store at -20CC or -80CC. Avoid repeated freeze. |
Purification Method |
Affinity-chromatography |
Modified |
Cancer; Tags & Cell Markers; Metabolism; Signal transduction |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.