Item no. |
CSB-PA996906-50ul |
Manufacturer |
Cusabio
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
4833442G10Rik antibody; AI430017 antibody; Atrogin 1 antibody; Atrogin-1 antibody; ATROGIN1 antibody; Atrophy gene 1 antibody; F box only protein 32 antibody; F-box only protein 32 antibody; F-box protein 32 antibody; FBX32_HUMAN antibody; fbxo25 antibody; FBXO32 antibody; FLJ32424 antibody; MAFbx antibody; MGC108443 antibody; MGC137646 antibody; MGC33610 antibody; Muscle atrophy F box antibody; Muscle atrophy F box protein antibody; Muscle atrophy F-box protein antibody, F-box protein 32 |
Similar products |
F-box protein 32 |
Available |
|
Immunogen Species |
Human |
UniprotID |
Q969P5 |
Immunogen |
Fusion protein of human FBXO32 |
Applications info |
ELISA, WB, IHC, ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 |
Dilution ratio 1 |
ELISA:1:1000-1:5000 |
Dilution ratio 2 |
WB:1:200-1:1000 |
Dilution ratio 3 |
IHC:1:25-1:100 |
Background |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Conjugate |
Non-conjugated |
Buffer |
-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antigen affinity purification |
General Research Areas |
Cardiovascular?Cell biology, Stem cells |
Initial Research Areas |
Cell Biology |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.