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UPF2 Antibody

UPF2 Antibody

Item no.	CSB-PA867186DSR2HU-50ul
Manufacturer	Cusabio
Amount	50ul
Category	Antibodies Immunohistochemistry ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DKFZp434D222 antibody; hUpf2 antibody; KIAA1408 antibody; MGC138834 antibody; MGC138835 antibody; Nonsense mRNA reducing factor 2 antibody; Regulator of nonsense transcripts 2 antibody; RENT2 antibody; RENT2_HUMAN antibody; Smg 3 antibody; Smg 3 homolog nonsense mediated mRNA decay factor antibody; Up-frameshift suppressor 2 homolog antibody; UPF2 antibody; UPF2 regulator of nonsense transcripts homolog antibody; UROC1 antibody; Urocanate hydratase antibody; Yeast Upf2p homolog antibody, Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2), UPF2, KIAA1408 RENT2
Similar products	UPF2, Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2), KIAA1408 RENT2
Available
Immunogen Species	Human
UniprotID	Q9HAU5
Immunogen	Recombinant Human Regulator of nonsense transcripts 2 protein (1153-1272AA)
Applications info	ELISA, IHC, Recommended dilution: IHC:1:20-1:200
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	IHC:1:20-1:200
Background	Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.
Conjugate	Non-conjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	Antigen Affinity Purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 9/13/2024

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