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MACROD1 Antibody, HRP conjugated

MACROD1 Antibody, HRP conjugated

Item no.	CSB-PA860244LB01HU-50ug
Manufacturer	Cusabio
Amount	50ug
Quantity options	100ug 50ug
Category	Antibodies ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
Conjugate/Tag	HRP
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MACROD1 antibody; LRP16 antibody; ADP-ribose glycohydrolase MACROD1 antibody; MACRO domain-containing protein 1 antibody; O-acetyl-ADP-ribose deacetylase MACROD1 antibody; EC 3.1.1.106 antibody; Protein LRP16 antibody; [Protein ADP-ribosylaspartate] hydrolase MACROD1 antibody; EC 3.2.2.- antibody; [Protein ADP-ribosylglutamate] hydrolase MACROD1 antibody; EC 3.2.2.- antibody, O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase), MACROD1, LRP16
Similar products	MACROD1, O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase), LRP16
Available
Immunogen Species	Human
UniprotID	Q9BQ69
Immunogen	Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA)
Applications info	ELISA
Background	Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.
Conjugate	HRP
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling, Cancer, Signal transduction
Initial Research Areas	Signal Transduction

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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