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MRAP2 Antibody

MRAP2 Antibody

Item no.	CSB-PA853421LA01HU-50ug
Manufacturer	Cusabio
Amount	50ug
Category	Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies small GTPases Ras Subfamily Rap Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MRAP2 antibody; C6orf117 antibody; Melanocortin-2 receptor accessory protein 2 antibody; MC2R accessory protein 2 antibody, Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2), MRAP2, C6orf117
Similar products	MRAP2, C6orf117, Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2)
Available
Immunogen Species	Human
UniprotID	Q96G30
Immunogen	Recombinant Human Melanocortin-2 receptor accessory protein 2 protein (66-205AA)
Applications info	ELISA, WB, IHC, IF, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	WB:1:1000-1:5000
Dilution ratio 3	IHC:1:20-1:200
Dilution ratio 4	IF:1:50-1:200
Background	Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R), however, additional evidences are required in vivo.
Conjugate	Non-conjugated
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Neuroscience, Signal transduction
Initial Research Areas	Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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