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AADAC Antibody

AADAC Antibody

Manufacturer	Cusabio
Category	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Format	Liquid
Applications	WB, IHC, ELISA
Amount	50ul
Host	Rabbit
Item no.	CSB-PA834531-50ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	AAAD_HUMAN antibody; Aada antibody; Aadac antibody; Arylacetamide deacetylase (esterase) antibody; Arylacetamide deacetylase antibody; CES5A1 antibody; DAC antibody, Arylacetamide deacetylase
Immunogen Species	Human
UniprotID	P22760
Immunogen	Fusion protein of human AADAC
Applications info	ELISA, WB, IHC, ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:100
Dilution ratio 1	ELISA:1:2000-1:5000
Dilution ratio 2	WB:1:500-1:2000
Dilution ratio 3	IHC:1:50-1:100
Background	Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.
Conjugate	Non-conjugated
Buffer	-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	Antigen affinity purification
General Research Areas	Metabolism, Signal transduction
Initial Research Areas	Signal Transduction

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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