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SKA3 Antibody

SKA3 Antibody

Item no.	CSB-PA816899LA01HU-50ug
Manufacturer	Cusabio
Amount	50ug
Category	Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C13orf3 antibody; RAMA1 antibody; SKA3 antibody; SKA3_HUMAN antibody; Spindle and kinetochore associated complex subunit 3 antibody; Spindle and kinetochore-associated protein 3 antibody, Spindle and kinetochore-associated protein 3, SKA3, C13orf3 RAMA1
Similar products	SKA3, Spindle and kinetochore-associated protein 3, C13orf3 RAMA1
Available
Immunogen Species	Human
UniprotID	Q8IX90
Immunogen	Recombinant Human Spindle and kinetochore-associated protein 3 protein (101-195AA)
Applications info	ELISA, IHC, IF, Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	IHC:1:200-1:500
Dilution ratio 3	IF:1:50-1:200
Background	Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
Conjugate	Non-conjugated
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Cell biology
Initial Research Areas	Cell Biology

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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