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BRAP Antibody

BRAP Antibody

Item no.	CSB-PA773793LA01HU-50ug
Manufacturer	Cusabio
Amount	50ug
Quantity options	100ug 20ug 50ug
Category	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cell Status Cytoskeleton Immunohistochemistry Western Blot ELISA Immunofluorescence Autophagy Primary Antibodies small GTPases Ras Subfamily Rap Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BRAP antibody; RNF52BRCA1-associated protein antibody; EC 2.3.2.27 antibody; BRAP2 antibody; Impedes mitogenic signal propagation antibody; IMP antibody; RING finger protein 52 antibody; RING-type E3 ubiquitin transferase BRAP2 antibody; Renal carcinoma antigen NY-REN-63 antibody, BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63), BRAP, RNF52
Similar products	BRAP, RNF52, BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63)
Available
Immunogen Species	Human
UniprotID	Q7Z569
Immunogen	Recombinant Human BRCA1-associated protein (13-124AA)
Applications info	ELISA, WB, IHC, IF, Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	WB:1:500-1:5000
Dilution ratio 3	IHC:1:200-1:500
Dilution ratio 4	IF:1:50-1:200
Background	Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Conjugate	Non-conjugated
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling, Signal transduction
Initial Research Areas	Epigenetics and Nuclear Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 10/4/2024

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