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CRTC2 Antibody

CRTC2 Antibody

Item no.	CSB-PA706631LA01HU-50ug
Manufacturer	Cusabio
Amount	50ug
Category	Oncology Neuroscience Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies By Organ Brain Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CREB regulated transcription coactivator 2 antibody; CREB-regulated transcription coactivator 2 antibody; CRTC2 antibody; CRTC2_HUMAN antibody; RP11-422P24.6 antibody; TORC-2 antibody; torc2 antibody; Transducer of CREB protein 2 antibody; Transducer of regulated cAMP response element-binding protein antibody; Transducer of regulated cAMP response element-binding protein (CREB) 2 antibody; Transducer of regulated cAMP response element-binding protein 2 antibody; Transducer of regulated CREB protein 2 antibody, CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2), CRTC2, TORC2
Similar products	CRTC2, TORC2, CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2)
Available
Immunogen Species	Human
UniprotID	Q53ET0
Immunogen	Recombinant Human CREB-regulated transcription coactivator 2 protein (180-372AA)
Applications info	ELISA, IHC, IF, Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	IHC:1:20-1:200
Dilution ratio 3	IF:1:50-1:200
Background	Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Conjugate	Non-conjugated
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling, Neuroscience, Cancer, Metabolism, Signal transduction
Initial Research Areas	Signal Transduction

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 8/23/2024

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