« Back
Home /
LRRC32 Antibody, Biotin conjugated

LRRC32 Antibody, Biotin conjugated

Item no.	CSB-PA618886LD01HU-50ug
Manufacturer	Cusabio
Amount	50ug
Category	Antibodies ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Biotin
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	D11S833E antibody; GARP antibody; Garpin antibody; Glycoprotein A repetitions predominant antibody; Leucine rich repeat containing 32 antibody; Leucine-rich repeat-containing protein 32 antibody; LRC32_HUMAN antibody; LRRC32 antibody, Transforming growth factor beta activator LRRC32 (Garpin) (Glycoprotein A repetitions predominant) (GARP) (Leucine-rich repeat-containing protein 32), LRRC32, D11S833E
Similar products	LRRC32, D11S833E, Transforming growth factor beta activator LRRC32 (Garpin) (Glycoprotein A repetitions predominant) (GARP) (Leucine-rich repeat-containing protein 32)
Available
Immunogen Species	Human
UniprotID	Q14392
Immunogen	Recombinant Human Transforming growth factor beta activator LRRC32 protein (301-500AA)
Applications info	ELISA
Background	Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).
Conjugate	Biotin
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Others
Initial Research Areas	Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CSB-PA618886LD01HU-50ug-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 50ug

available

Delivery expected until 9/13/2024

Express Delivery: Save 3 days

Compare

Add to wishlist

Recommend by mail