Item no. |
CSB-PA613427ESR1HU-50ul |
Manufacturer |
Cusabio
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ATX antibody; ATX X antibody; Autotaxin antibody; Autotaxin t antibody; E NPP 2 antibody; E-NPP 2 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 antibody; Enpp2 antibody; ENPP2_HUMAN antibody; Extracellular lysophospholipase D antibody; FLJ26803 antibody; LysoPLD antibody; NPP2 antibody; PD IALPHA antibody; PDNP2 antibody; Phosphodiesterase I alpha antibody; Phosphodiesterase I/nucleotide pyrophosphatase 2 antibody; Plasma lysophospholipase D antibody, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD), ENPP2, ATX PDNP2 |
Similar products |
ENPP2, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD), ATX PDNP2 |
Available |
|
Immunogen Species |
Human |
UniprotID |
Q13822 |
Immunogen |
Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 protein (564-863AA) |
Applications info |
ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
Dilution ratio 1 |
ELISA:1:2000-1:10000 |
Dilution ratio 2 |
IHC:1:20-1:200 |
Background |
Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor. |
Conjugate |
Non-conjugated |
Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antigen Affinity Purified |
General Research Areas |
Neuroscience, Cancer, Cardiovascular, Metabolism, Signal transduction |
Initial Research Areas |
Cardiovascular |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.