Item no. |
CSB-PA558008-50ul |
Manufacturer |
Cusabio
|
Amount |
50ul |
Quantity options |
100ul
50ul
|
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Macropain chain Z antibody; Multicatalytic endopeptidase complex chain Z antibody; Proteasome (prosome macropain) subunit beta type 7 antibody; Proteasome beta 7 subunit antibody; Proteasome catalytic subunit 2 antibody; Proteasome subunit alpha antibody; Proteasome subunit beta 7 antibody; Proteasome subunit beta type-7 antibody; Proteasome subunit Z antibody; PSB7_HUMAN antibody; PSMB7 antibody; PUP1 antibody; Z antibody, proteasome (prosome, macropain) subunit, beta type, 7 |
Similar products |
7, beta type, proteasome (prosome, macropain) subunit |
Available |
|
Immunogen Species |
Human |
UniprotID |
Q99436 |
Immunogen |
Fusion protein of human PSMB7 |
Applications info |
ELISA, WB, IHC, ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Dilution ratio 1 |
ELISA:1:2000-1:5000 |
Dilution ratio 2 |
WB:1:500-1:2000 |
Dilution ratio 3 |
IHC:1:25-1:100 |
Background |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. |
Conjugate |
Non-conjugated |
Buffer |
-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antigen affinity purification |
General Research Areas |
Cell biology, Metabolism, Signal transduction |
Initial Research Areas |
Signal Transduction |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.