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Phospho-FGFR1/FGFR2 (Tyr463/466) Antibody

Phospho-FGFR1/FGFR2 (Tyr463/466) Antibody

Item no.	CSB-PA443701
Manufacturer	Cusabio
Amount	100ul
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies Astrocytoma By Organ Bladder Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Basic fibroblast growth factor receptor 1 antibody; bFGF-R-1 antibody; BFGFR antibody; CD331 antibody; CEK antibody; FGFBR antibody; FGFR 1 antibody; FGFR-1 antibody; FGFR1 antibody; FGFR1/PLAG1 fusion antibody; FGFR1_HUMAN antibody; fibroblast growth factor receptor 1 antibody; FLG antibody; FLT-2 antibody; FLT2 antibody; Fms-like gene antibody; Fms-like tyrosine kinase 2 antibody; fms-related tyrosine kinase 2 antibody; HBGFR antibody; heparin-binding growth factor receptor antibody; HH2 antibody; HRTFDS antibody; hydroxyaryl-protein kinase antibody; KAL2 antibody; N-SAM antibody; OGD antibody; Proto-oncogene c-Fgr antibody, BFGFR, CEK, FLG, CD331, FLT2
Similar products	BFGFR, CEK, FLG, FLT2, CD331
Available
Immunogen Species	Human
UniprotID	P11362/P21802
Immunogen	Peptide sequence around phosphorylation site of tyrosine 463/466(S-E-Y(p)-E-L) derived from Human FGFR1/2.
Applications info	ELISA, WB, WB:1:500-1:1000
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	WB:1:500-1:1000
Background	The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Itoh N., Biochem. Biophys. Res. Commun. 169:680-685(1990). Dionne C.A., EMBO J. 9:2685-2692(1990). Johnson D.E., Mol. Cell. Biol. 10:4728-4736(1990).
Conjugate	Non-conjugated
Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
General Research Areas	Epigenetics and Nuclear Signaling?Neuroscience?Cancer?Cardiovascular, Signal transduction
Initial Research Areas	Cardiovascular

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 9/27/2024