Item no. |
CSB-PA356041LD01HTO-50ug |
Manufacturer |
Cusabio
|
Amount |
50ug |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
ELISA |
Specific against |
other |
Host |
Rabbit |
Isotype |
IgG |
Conjugate/Tag |
Biotin |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
F antibody; Fusion glycoprotein F0 antibody; Protein F) [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; Fusion glycoprotein F2; Fusion glycoprotein F1] antibody, Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2', Interchain peptide, Fusion glycoprotein F2, Fusion glycoprotein F1], F, Human respiRatory syncytial virus A |
Similar products |
F, Fusion glycoprotein F1], Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2', Interchain peptide, Fusion glycoprotein F2 |
Available |
|
Species Information |
Human respiRatory syncytial virus A |
Immunogen Species |
Human respiratory syncytial virus A |
UniprotID |
P03420 |
Immunogen |
Recombinant Human respiratory syncytial virus A Fusion glycoprotein F0 protein (27-529AA) |
Applications info |
ELISA |
Background |
During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2 (PubMed:18216092). Interacts directly with heparan sulfate and may participates in virus attachment (PubMed:10864656). Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity (PubMed:11493675). Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis (PubMed:12663767). |
Conjugate |
Biotin |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
>95%, Protein G purified |
General Research Areas |
Others |
Initial Research Areas |
Others |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.