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SCN5A Antibody

SCN5A Antibody

Item no.	CSB-PA280563
Manufacturer	Cusabio
Amount	100ul
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot ELISA Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit antibody; CDCD2 antibody; CMD1E antibody; CMPD2 antibody; HB1 antibody; HB2 antibody; HBBD antibody; HH1 antibody; ICCD antibody; IVF antibody; LQT3 antibody; PFHB1 antibody; Scn5a (gene name) antibody; Scn5a antibody; SCN5A_HUMAN antibody; Sodium channel protein cardiac muscle alpha subunit antibody; Sodium channel protein cardiac muscle subunit alpha antibody; Sodium channel protein type 5 subunit alpha antibody; Sodium channel protein type V alpha subunit antibody; Sodium channel protein type V subunit alpha antibody; SSS1 antibody; VF1 antibody; Voltage gated sodium channel alpha subunit Nav1.5 antibody; Voltage-gated sodium channel subunit alpha Nav1.5 antibody, CIN5, HH1, SCN5A, Sodium channel protein, cardiac muscle alpha-subunit
Similar products	SCN5A, HH1, CIN5, Sodium channel protein, cardiac muscle alpha-subunit
Available
Immunogen Species	Human
UniprotID	Q14524
Immunogen	Synthesized peptide derived from human sodium channel.
Applications info	ELISA, WB, IHC, WB:1:500-1:3000, IHC:1:50-1:100
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	WB:1:500-1:3000
Dilution ratio 3	IHC:1:50-1:100
Background	This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na+ channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels. Sebastian K.G. Maier, Circulation, Mar 2004, 109: 1421 - 1427. T.R. Cummins, Neurology, Jan 2003, 60: 224 - 229. Christopher A. Ahern, Circ. Res., May 2005, 96: 991 - 998. Jyoti Dhar Malhotra, Circulation, Mar 2001, 103: 1303 - 1310.
Conjugate	Non-conjugated
Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
General Research Areas	Neuroscience, Cardiovascular
Initial Research Areas	Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 1/17/2025