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Phospho-IRS1 (Ser307) Antibody

Phospho-IRS1 (Ser307) Antibody

Item no.	CSB-PA224848
Manufacturer	Cusabio
Amount	100ul
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Neural Adhesion Molecules Antibodies Immunohistochemistry ELISA Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HIRS 1 antibody; HIRS1 antibody; Insulin receptor substrate 1 antibody; IRS 1 antibody; IRS-1 antibody; IRS1 antibody; IRS1_HUMAN antibody; OTTHUMP00000164234 antibody, HIRS-1
Similar products	HIRS-1
Available
Immunogen Species	Human
UniprotID	P35568
Immunogen	Peptide sequence around phosphorylation site of serine 307(T-E-S(p)-I-T) derived from Human IRS-1.
Applications info	ELISA, IHC, IHC:1:50-1:100
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	IHC:1:50-1:100
Background	, May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit ,
Conjugate	Non-conjugated
Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
General Research Areas	Neuroscience?Cancer?Cardiovascular, Tags & Cell Markers, Metabolism, Signal transduction
Initial Research Areas	Tags & Cell Markers

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 9/6/2024

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