Item no. |
CSB-PA208276 |
Manufacturer |
Cusabio
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
FGFR signaling adaptor SNT antibody; FGFR signalling adaptor antibody; FGFR substrate 2 antibody; FGFR-signaling adaptor SNT antibody; Fibroblast growth factor receptor substrate 2 antibody; FRS 2 antibody; FRS2 antibody; FRS2_HUMAN antibody; FRS2A antibody; FRS2alpha antibody; SNT 1 antibody; SNT antibody; SNT-1 antibody; SNT1 antibody; Suc 1 Associated Neurotrophic Factor Target antibody; Suc1 associated neurotrophic factor target 1 antibody; Suc1-associated neurotrophic factor target 1 antibody, FGFR signalling adaptor, FGFR signalling adaptor SNT-1, SNT-1, SNT2, SUC1-associated neurotrophic factor target |
Similar products |
SNT-1, FGFR signalling adaptor, SNT2, FGFR signalling adaptor SNT-1, SUC1-associated neurotrophic factor target |
Available |
|
Immunogen Species |
Human |
UniprotID |
Q8WU20 |
Immunogen |
Synthesized non-phosphopeptide derived from human FRS2 around the phosphorylation site of tyrosine 196 (H-T-Y(p)-V-N). |
Applications info |
ELISA, WB, WB:1:500-1:3000 |
Dilution ratio 1 |
ELISA:1:2000-1:10000 |
Dilution ratio 2 |
WB:1:500-1:3000 |
Background |
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
The MGC Project Team, Genome Res. 14:2121-2127(2004). Xu H., J. Biol. Chem. 273:17987-17990(1998). Meakin S.O., J. Biol. Chem. 274:9861-9870(1999). |
Conjugate |
Non-conjugated |
Buffer |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
General Research Areas |
Signal transduction |
Initial Research Areas |
Signal Transduction |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.