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RAB7B Antibody, HRP conjugated

RAB7B Antibody, HRP conjugated

Item no.	CSB-PA019220LB01HU-50ug
Manufacturer	Cusabio
Amount	50ug
Quantity options	100ug 50ug
Category	Neuroscience Targets for Rodent Neurosciences Antibodies Cell Biology Cytoskeleton ELISA Primary Antibodies small GTPases Ras Subfamily Rab Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
Conjugate/Tag	HRP
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MGC16212 antibody; MGC9726 antibody; RAB7 antibody; rab7B antibody; RAB7B; member RAS oncogene family antibody; RAB7B_HUMAN antibody; Ras related protein Rab 7b antibody; Ras-related protein Rab-7B antibody, Ras-related protein Rab-7b, RAB7B
Similar products	RAB7B, Ras-related protein Rab-7b
Available
Immunogen Species	Human
UniprotID	Q96AH8
Immunogen	Recombinant Human Ras-related protein Rab-7b protein (100-199AA)
Applications info	ELISA
Background	Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
Conjugate	HRP
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Tags & Cell Markers, Signal transduction
Initial Research Areas	Tags & Cell Markers

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Delivery expected until 10/4/2024

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