« Back
Home /
NF2 Antibody

NF2 Antibody

Item no.	CSB-PA015741LA01HU-50ug
Manufacturer	Cusabio
Amount	50ug
Quantity options	100ug 20ug 50ug
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Mesothelioma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Microglia Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ACN antibody; BANF antibody; Bilateral acoustic neuroma antibody; MERL_HUMAN antibody; Merlin antibody; Moesin ezrin radixin like protein antibody; Moesin ezrin radizin like antibody; Moesin-ezrin-radixin-like protein antibody; Neurofibromatosis 2 antibody; Neurofibromatosis type 2 antibody; Neurofibromatosis2 antibody; Neurofibromin 2 antibody; Neurofibromin-2 antibody; Neurofibromin2 antibody; NF 2 antibody; Nf2 antibody; SCH antibody; Schwannomerlin antibody; Schwannomin antibody, Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin), NF2, SCH
Similar products	NF2, SCH, Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Available
Immunogen Species	Human
UniprotID	P35240
Immunogen	Recombinant Human Merlin protein (230-414AA)
Applications info	ELISA, WB, IHC, IF, Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	WB:1:2000-1:5000
Dilution ratio 3	IHC:1:20-1:200
Dilution ratio 4	IF:1:50-1:200
Background	Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-DCAF1/DCAF1 E3 ubiquitin-protein ligase complex.
Conjugate	Non-conjugated
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling, Neuroscience, Cancer, Signal transduction
Initial Research Areas	Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50ug

available

Delivery expected until 10/4/2024

Express Delivery: Save 2 days

Compare

Add to wishlist

Recommend by mail