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ITGAV Antibody, FITC conjugated

ITGAV Antibody, FITC conjugated

Item no.	CSB-PA011877LC01HU-50ug
Manufacturer	Cusabio
Amount	50ug
Quantity options	100ug 50ug
Category	Oncology Neuroscience Neural Adhesion Molecules Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies By Cell Type Carcinoma Cell Biology ELISA Cell Stainings ECM Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
Conjugate/Tag	FITC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	antigen identified by monoclonal antibody L230 antibody; CD 51 antibody; CD51 antibody; DKFZp686A08142 antibody; Integrin alpha five antibody; integrin alpha V beta 3 antibody; Integrin alpha-5 antibody; integrin alpha-V antibody; Integrin alpha-V light chain antibody; integrin alphaVbeta3 antibody; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody; ITAV_HUMAN antibody; ITGAV antibody; MSK 8 antibody; Msk8 antibody; Vitronectin receptor subunit alpha antibody; VNRA antibody; VTNR antibody, Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain, Integrin alpha-V light chain], ITGAV, MSK8 VNRA VTNR
Similar products	ITGAV, Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain, Integrin alpha-V light chain], MSK8 VNRA VTNR
Available
Immunogen Species	Human
UniprotID	P06756
Immunogen	Recombinant Human Integrin alpha-V protein (775-885AA)
Applications info	ELISA
Background	The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:23125415). ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed:18441324). ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:19578119). ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGAV:ITGB3 and ITGAV:ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881).
Conjugate	FITC
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	>95%, Protein G purified
General Research Areas	Cancer, Cardiovascular, Microbiology, Signal transduction, Stem cells
Initial Research Areas	Cardiovascular

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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