Item no. |
CSB-PA007537ESR1HU-50ul |
Manufacturer |
Cusabio
|
Amount |
50ul |
Quantity options |
100ul
50ul
|
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, IHC, ELISA |
Specific against |
Human, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
eIF-3-gamma antibody; eIF3 gamma antibody; eIF3 p40 antibody; eIF3 p40 subunit antibody; eIF3h antibody; EIF3H_HUMAN antibody; EIF3S3 antibody; Eukaryotic translation initiation factor 3 subunit 3 antibody; Eukaryotic translation initiation factor 3 subunit H antibody; MGC102958 antibody, Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit), EIF3H, EIF3S3 |
Similar products |
EIF3H, EIF3S3, Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit) |
Available |
|
Immunogen Species |
Human |
UniprotID |
O15372 |
Immunogen |
Recombinant Human Eukaryotic translation initiation factor 3 subunit H protein (80-340AA) |
Applications info |
ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
Dilution ratio 1 |
ELISA:1:2000-1:10000 |
Dilution ratio 2 |
WB:1:500-1:2000 |
Dilution ratio 3 |
IHC:1:20-1:200 |
Background |
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. |
Conjugate |
Non-conjugated |
Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antigen Affinity Purified |
General Research Areas |
Epigenetics and Nuclear Signaling |
Initial Research Areas |
Epigenetics and Nuclear Signaling |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.