Comparison

CRSP130 (F26) polyclonal antibody

Item no. BS9128-100
Manufacturer Bioworld Technology, Inc
Amount 100ul
Category
Type Antibody Polyclonal
Applications WB, IHC
Specific against Human, Mouse, Rat
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Mediator of RNA polymerase II transcription subunit 23, Activator-recruited cofactor 130 kDa component, ARC130, Cofactor required for Sp1 transcriptional activation subunit 3, CRSP complex subunit 3, Mediator complex subunit 23, Protein sur-2 homolog, hSu
Similar products CRSP130
Available
Swiss-Prot
Q9ULK4
Application all
WB: 1:500ca.1:1000
IHC: 1:50ca.1:200
Background
CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits. Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS. CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits also associate with larger multimeric co-activator complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription.
Product
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity
CRSP130 (F26) pAb detects endogenous levels of CRSP130 protein.
WB
Western blot (WB) analysis of CRSP130 (F26) pAb at 1:500 dilution
Lane1:MCF-7 whole cell lysate
Lane2:Raw264.7 whole cell lysate
Lane3:PC12 whole cell lysate
IHC
Immunohistochemistry (IHC) analyzes of CRSP130 (F26) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.
BiowMW
ca. 156 kDa
Note
For research use only, not for use in diagnostic procedure.
Alternative Name
Mediator of RNA polymerase II transcription subunit 23, Activator-recruited cofactor 130 kDa component, ARC130, Cofactor required for Sp1 transcriptional activation subunit 3, CRSP complex subunit 3, Mediator complex subunit 23, Protein sur-2 homolog, hSur-2, Transcriptional coactivator CRSP130, Vitamin D3 receptor-interacting protein complex 130 kDa component, DRIP130, MED23, ARC130, CRSP3, DRIP130, KIAA1216, SUR2
Immunogen
Synthetic peptide, corresponding to the N-terminual of Human CRSP130.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ul
Available: In stock
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