Item no. |
BS91235-50 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
50ul |
Category |
|
Type |
Antibody Primary |
Applications |
WB, IHC, ICC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
SRSF3, SFRS3, SRP20, arginine/serine-rich 3, Pre mRNA splicing factor SRP20, Pre-mRNA-splicing factor SRP20, Serine/arginine-rich splicing factor 3, Splicing factor, Splicing factor arginine/serine rich 20 kD, Splicing factor arginine/serine rich 3, SRp20 |
Available |
|
Swiss-Prot |
P84103 Human; P84104 Mouse; Entrez Gene: 361814 Rat |
Application_all |
WB:1:500-1:2, 000 ICC:1:50-1:200 IHC:1:100-1:500 |
Background |
Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export (PubMed:28984244). RNA-binding is semi-sequence specific. |
Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Purification And Purity |
Protein A purified. |
Storage And Stability |
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles. |
Specificity |
SFRS3 polyclonal antibody detects endogenous levels of SFRS3 protein. |
BiowMW |
19 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Immunogen |
Full length recombinant protein. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.