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PDIA6 polyclonal antibody

PDIA6 polyclonal antibody

Item no.	BS91044-50
Manufacturer	Bioworld Technology, Inc
Amount	50ul
Category	Antibodies Cell Biology Cell Status Flow Cytometry Western Blot Immunofluorescence Immunocytochemistry Senescence Primary Antibodies
Type	Antibody Primary
Applications	WB, FC, IF, ICC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ER protein 5, ERp5, PDIA6, Endoplasmic reticulum protein 5, ER protein 5, ERp5, P5, Pdia6, PDIA6, Protein disulfide isomerase A6, Protein disulfide isomerase associated 6, Protein disulfide isomerase family A member 6, Protein disulfide isomerase P5, Prot
Available
Swiss-Prot	Q15084(Human) Q922R8(Mouse) Q63081(Rat)
Application_all	WB:1:1, 000-1:2, 000 FC:1:50-1:100 ICC:1:100-1:500
Background	Endoplasmic reticulum proteins (ERps) are widely expressed proteins that localize to the ER and may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases or phospholipases. ERp5, also known as PDIA6 (protein disulfide isomerase family A, member 6) or TXNDC7 is a 440 amino acid protein that contains two thioredoxin domains and belongs to the protein disulfide isomerase family. Localized to the melanosome, as well as to the lumen of the endoplasmic reticulum, ERp5 functions to catalyze the rearrangement of disulfide bonds in a variety of different proteins. Via its catalytic activity, ERp5 is able to reduce the disulfide bond that binds MICA to tumor cells, thereby releasing MICA and reducing the rate of tumor expansion. Multiple isoforms of ERp5 exist due to alternative splicing events.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	PDIA6 polyclonal antibody detects endogenous levels of PDIA6 protein.
BiowMW	48 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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