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NLRP3 polyclonal antibody

NLRP3 polyclonal antibody

Item no.	BS90948-50
Manufacturer	Bioworld Technology, Inc
Amount	50ul
Category	Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Applications	WB, FC, IHC, ICC
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CLR1.1, NLRP3, C1orf7, CIAS1, NALP3, PYPAF1, AGTAVPRL, AII/AVP, Angiotensin/vasopressin receptor AII/AVP like, Angiotensin/vasopressin receptor AII/AVP-like, C1orf7, Caterpiller protein 1.1, CIAS 1, CIAS1, CLR1.1, Cold autoinflammatory syndrome 1, Cold au
Available
Swiss-Prot	Q96P20(Human) Q8R4B8(Mouse)
Application_all	WB:1:500-1:2, 000 ICC:1:500-1:2, 000 IHC:1:50-1:200 FC:1:50-1:100
Background	Cryopyrin interacts selectively with apoptosis associated specklike protein containing a CARD domain (ASC). This complex may function as an upstream activator of NFkB signaling and caspase-1 activation. The complex also inhibits TNFa induced activation and nuclear translocation of RelA/NFkB p65. Mutations in Cryopyrin and Pyrin proteins are responsible for several autoinflammatory disorders in humans, including familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS) and chronic infantile neurologic cutaneous and articular syndrome (CINCA).
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	Peptide affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	NLRP3 polyclonal antibody detects endogenous levels of NLRP3 protein.
BiowMW	85 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Peptide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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