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IP3 Receptor polyclonal antibody

IP3 Receptor polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, IHC
Amount	50ul
Host	Rabbit
Item no.	BS90733-50
Targets	ITPR1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1, 4, 5-trisphosphate receptor, 5-trisphosphate receptor type 1, DKFZp313E1334, DKFZp313N1434, inositol 1 4 5 triphosphate receptor type 1, Inositol 1 4 5 trisphosphate Receptor Type 1, Inositol 1, InsP
Swiss-Prot	Q14643(Human) P11881(Mouse) P29994(Rat)
Application_all	WB:1:500 IHC:1:50-1:200
Background	Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1, 4, 5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	IP3 Receptor polyclonal antibody detects endogenous levels of IP3 Receptor protein.
BiowMW	314 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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