Item no. |
BS90689-100 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
100ul |
Category |
|
Type |
Antibody Primary |
Applications |
WB, IHC |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
IBP-2, IGF-binding protein 2, IGFBP-2, IGFBP2, BP2, IBP2, BP 2, BP2, IBP 2, IBP-2, IBP2, IBP2, IGF binding protein 2, IGF BP53, IGF-binding protein 2, IGFBP 2, IGFBP-2, IGFBP2, IGFBP53, Insulin like growth factor binding protein 2 36kDa, Insulin like grow |
Available |
|
Swiss-Prot |
P18065(Human) |
Application_all |
WB:1:500-1:2, 000 IHC:1:50-1:200 |
Background |
The Insulin-like growth factor-binding proteins (IGFBPs), a family of homologous proteins that have co-evolved with the IGFs, serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. Physical association of the IGFBPs with IGF influences the bio-availability of the growth factors, and their concentration and distribution in the extracellular environment. The IGFBPs also appear to have biological activity independent of the IGFs. Seven IGFBPs have been described, each differing in their tissue distribution, half-lives and modulation of IGF interactions with their receptors. IGFBP1 is negatively regulated by Insulin production. The IGFBP1 gene is expressed at a high level during fetal liver development and in response to nutritional changes and diabetes. IGFBP2, which may function as a chaperone, escorting IGFs to their target tissues, is expressed in several human tissues including fetal eye and fetal brain. |
Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Purification And Purity |
ProA affinity purified |
Storage And Stability |
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles. |
Specificity |
IGFBP2 polyclonal antibody detects endogenous levels of IGFBP2 protein. |
BiowMW |
35 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Immunogen |
Recombinant protein |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.