Comparison

Human IgM polyclonal antibody

Item no. BS90677-50
Manufacturer Bioworld Technology, Inc
Amount 50 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Primary
Applications WB, IP, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Conjugate/Tag Unconjugated
Purity ProA affinity purified
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias IGHM, Immunoglobin heavy chain constant region mu edit item name - Immunoglobin heavy chain mu constant region, Immunoglobin heavy chain constant region mu, AGM1, Constant region of heavy chain of IgM, DKFZp686I15196, DKFZp686I15212, FLJ00385, Ig mu chain C region, IGHM, IgM heavy chain constant region, Immunoglobin heavy constant mu, Immunoglobulin mu, MGC104996, MGC52291, MU, VH,
Available
Application Notes
WB:1:1, 000-1:5, 000
IHC:1:50-1:200
Background
Immunoglobulin M (IgM) is the largest circulating antibody molecule in humans. It consists of a heavy chain (?-chain) and a light chain (κ- or λ-chain), as well as 5 base units and 10 binding sites, though it cannot bind all 10 simultaneously because of steric hindrance. IgM chain C refers to the constant region of the IgM heavy chain that is involved in immune regulation. IgM forms polymers by covalently linking multiple immunoglobulins together with disulfide bonds. It normally exists as a pentamer, but occasionally as a hexamer. Because of its polymeric nature, IgM has high avidity, and it is especially effective at complement activation. Due to its large size, IgM does not diffuse well, and it is found in the interstitium in very low amounts. IgM is mainly found in serum; however, because of the J chain, it is also important as a secretory immunoglobulin. IgM is the first immunoglobulin expressed by mature B cells, and it normally appears early in the course of an infection and does not reappear after further exposure.
Manufacturer - Product
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Manufacturer - Specificity
Human IgM polyclonal antibody detects endogenous levels of Human IgM protein.
Molecular Weight
75 kDa
Note
For research use only, not for use in diagnostic procedure.
Immunogen
recombinant protein
Modification
Unmodification

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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