Item no. |
BS90612-100 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
100ul |
Category |
|
Type |
Antibody Primary |
Applications |
WB, IP, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
HBA1, HBA2, Alpha 1 globin, Alpha globin, Alpha one globin, Alpha-globin, HBA, HBA1, HBA2, Hemoglobin alpha 1, Hemoglobin alpha 1 chain, Hemoglobin alpha 1 globin chain, Hemoglobin alpha 2, Hemoglobin alpha chain, Hemoglobin subunit alpha, MGC126895, MGC1 |
Available |
|
Swiss-Prot |
P69905(Human) P01942(Mouse) P01946(Rat) |
Application_all |
WB:1:1, 000 IHC:1:10-1:50 |
Background |
Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The alpha (16p13.3; 5'-zeta-pseudoz-pseudo alpha2-pseudo alpha1-alpha2-alpha1-?1-3') and beta (11p15.5) globin loci determine the basic hemoglobin structure. The globin portion of hemoglobin consists of two alpha chains and two beta chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between alpha and beta chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the alpha1-beta2 cleavage plane. When the two alpha1-beta2 interfaces are closely bound, hemoglobin has a low affinity for oxygen. Hb A, which contains two alpha chains plus two beta chains, comprises 97% of total circulating hemoglobin. The remaining 3% of total circulating hemoglobin is comprised of Hb A-2, which consists of two alpha chains plus two delta chains, and fetal hemoglobin (Hb F), which consists of two alpha chains together with two gamma chains. |
Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Purification And Purity |
ProA affinity purified |
Storage And Stability |
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles. |
Specificity |
HBA1 polyclonal antibody detects endogenous levels of HBA1 protein. |
BiowMW |
15 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Immunogen |
recombinant protein |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.