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Gemin 1 polyclonal antibody

Gemin 1 polyclonal antibody

Item no.	BS90572-100
Manufacturer	Bioworld Technology, Inc
Amount	100ul
Category	Antibodies Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Primary
Applications	WB, IP, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SMN1, SMN, SMNT, BCD541, Component of gems 1, Gemin 1, Gemin-1, OTTHUMP00000125198, OTTHUMP00000223567, OTTHUMP00000223568, OTTHUMP00000224066, OTTHUMP00000226924, SMA 1, SMA 2, SMA 3, SMA 4, SMA, SMA, SMA1, SMA2, SMA3, SMA4, SMN, SMN, SMN1, SMN2, SMNT, S
Available
Swiss-Prot	Q16637(Human)
Application_all	WB:1:500-1:1, 000 IHC:1:50-1:200 IP:1:10-1:50
Background	The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Ensures the correct splicing of U12 intron-containing genes that may be important for normal motor and proprioceptive neurons development. Also required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Specificity	Gemin 1 polyclonal antibody detects endogenous levels of Gemin 1 protein.
BiowMW	32 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein within human Gemin 1 aa 1-200.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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