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Eg5 polyclonal antibody

Eg5 polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Signaling Antibodies Cell Biology Cytoskeleton Immunoprecipitation Western Blot Motor proteins Primary Antibodies
Type	Antibody Primary
Specific against	Human
Applications	WB, IP
Amount	100ul
Host	Rabbit
Item no.	BS90447-100
Targets	KIF11
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	TR-interacting protein 5, TRIP-5, KIF11, EG5, KNSL1, TRIP5, EG5, HKSP, KIF11, KIF11, Kinesin family member 11, Kinesin like protein 1, Kinesin-like protein 1, Kinesin-like protein KIF11, Kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5
Swiss-Prot	P52732(Human)
Application_all	WB:1:500-1:2, 000 IP:1:10-1:50
Background	Eukaryotes contain a superfamily of microtubule-based motor proteins comprising kinesin and a number of related proteins that are thought to participate in various forms of intracellular motility, including cell division and organelle transport. KIF11(also known as kinesin family member 11, Eg5 or TRIP5) is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of KIF11 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. KIF11 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). KIF11 is also known to be a member of the thyroid receptor interacting protein (Trip) family, and interacts with the thyroid hormone receptor only in the presence of thyroid hormone.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	Eg5 polyclonal antibody detects endogenous levels of Eg5 protein.
BiowMW	119 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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