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Bax polyclonal antibody

Bax polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Autophagy Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, FC, IP, IHC
Amount	50ul
Host	Rabbit
Item no.	BS90121-50
Targets	BAX ;;BCL2
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	Bcl2-L-4, Apoptosis regulator BAX, BAX, Bax-protein, BAX, BAXA, Baxdelta2G9, Baxdelta2G9omega, Baxdelta2omega, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, Bcl2-L-4,
Swiss-Prot	Q07812(Human) Q07813(Mouse) Q63690(Rat)
Application_all	WB:1:1, 000-1:5, 000 IHC:1:50-1:200 FC:1:50-1:100
Background	The Bcl-2 gene was isolated at the chromosomal breakpoint of t-bearing follicular B cell lymphomas. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 is localized to outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes. A related protein, designated Bax (Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activity of Bcl-2.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	Bax polyclonal antibody detects endogenous levels of Bax protein.
BiowMW	21, 15 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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