Item no. |
BS90116-100 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
100ul |
Category |
|
Type |
Antibody Primary |
Applications |
WB, IF, IP, IHC, ICC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
BAF57, SMARCE1, BAF57, BRG1 associated factor 57, BRG1-associated factor 57, Chromatin remodeling complex BRG1 associated factor 57, FLJ35648, SMARCE 1, SMARCE1, SMCE1, SWI/SNF related matrix associated actin dependent regulator of chromatin e1, SWI/SNF r |
Available |
|
Swiss-Prot |
Q969G3(Human) O54941(Mouse) Q56A18(Rat) |
Application_all |
WB:1:500-1:2, 000 ICC/IF:1:50-1:200 IHC:1:50-1:200 IP:1:50-1:200 |
Background |
The SWI/SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF1 or SNF2alpha) and Brg-1 (also designated SNF2 or SNF2beta) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. In higher eukaryotes, BAF57 is also a critical component of the SWI/ SNF complex. BAF57 contains a high-mobility-group (HMG) domain adjacent to a kinesin-like region and is a DNA-binding subunit of the SWI/SNF complex. The human BAF57 gene maps within the q12-25 region of chromosome 17, a gene-rich area implicated in breast and ovarian cancers. |
Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Purification And Purity |
ProA affinity purified |
Storage And Stability |
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles. |
Specificity |
BAF57 polyclonal antibody detects endogenous levels of BAF57 protein. |
BiowMW |
47 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Immunogen |
Recombinant protein within human BAF57 aa 1-200. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.